Cutaneous Manifestations of Monoclonal Gammopathy • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic spicules • Intravascular lg deposits: Type I cryoglobulinemia • Autoantibody activity: Type II cryoglobulinemia, Cold agglutinin disease, Xanthomatosis • Cytokine secretion: POEMS syndrome, Syndrome Schnitzler • Unknown mechanism: Scleromyxoedema, Acquired cutis laxa, TEMPI syndrome, Pyoderma gangrenosum By Dr. Nader Yatim @NaderYatim #monoclonal #gammopathy #Cutaneous #manifestations #dermatology #skin #clinical
