Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): • Procainamide ~20% for 1 year of treatment • Hydralazine ~5-8% / 1 year Moderate (1-5%) to low (0.1-1%) Risk: • Quinidine, Captopril, anti-TNFa, Interferon-a, Methyldopa, Sulfasalazine, Propylthiouracil, Acebutolol, Chlorpromazine, Isoniazid, Minocycline, Carbamazepine, Terbinafin Low risk (0-0.1%) to very low (<0.1%) risk: • Disopyramide, Propafenone, Amiodarone, Atenolol, Labetalol, Streptomycin, Pindolol, Minoxidil, Prazosin, Enalapril, Lisinopril, Nalidixic acid, Clonidine, Clozapine, Sertraline, Quinine, Hydrochlorothiazide, Clobazam, Phenytoin, Primidone, Ethosuximide, Valproic acid, Phenylbutazone, Mesalazine, Zafirlukast, Chlorthalidone, Sulfamethoxazole, Simvastatin, Atorvastatin Dr. Laurent ARNAUD @Lupusreference #DrugInduced #SLE #Systemic #Lupus #Erythematosus #medications #drugs #pharmacology #risk #differential #diagnosis #rheumatology
