Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and fingers, or pain everywhere) 2) A rash on the face (many differential diagnoses, including the very common rosacea) 3) Limb oedema leading to the discovery of proteinuria/hematuria 4) Always with pericarditis (search ANA) ; sometimes « viral pericarditis » is...lupus 5) Always with pleurisy (search ANA) [especially if not responsive to antibiotics] 6) An annular rash on the body or in photoexposed areas (photosensitivity) 7) Always in case of psychosis or epilepsis in a young person (search ANA*) 8) Always in case of cytopenia (search ANA and aPL) 9) Unexplained fever, when infection has been ruled out, including in children (pediatric SLE) 10) When confronted to unexplained manifestations especially with several organs involved Dr. Laurent ARNAUD @Lupusreference #lupus #diagnosis #sle #clues #system #erythematosus #rheumatology
