EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring alopecia, Oral ulcers, Subacute cutaneous or discoid lupus, Acute cutaneous lupus • Arthritis domain: Synovitis or tenderness in at least 2 joints • Neurologic domain: Delirium, Psychosis, Seizure • Serositis domain: Pleural or pericardial effusion, Acute pericarditis • Hematologic domain: Leukopenia, Thrombocytopenia, Autoimmune hemolysis • Renal domain: Proteinuria > 0.5 g/24 hr, Class II or V lupus nephritis, Class Ill or IV lupus nephritis Immunologic domains: • Antiphospholipid antibody domain: Anticardiolipin IgG > 40 GPL or anti-ß2GPI IgG > 40 units or lupus anticoagulant • Complement proteins domain: Low C3 or low C4, Low C3 and low C4 • Highly specific antibodies domain: Anti-dsDNA antibody, Anti-Sm antibody Dr. Laurent ARNAUD @Lupusreference #EULARACR #Classification #Criteria #SLE #Systemic #Lupus #Erythematosus #diagnosis #rheumatology
