Diabetic Myonecrosis (Diabetic Muscle Infarction) • Spontaneous ischemic necrosis of skeletal muscle (anterior thigh or calf) • Rare complication of longstanding uncontrolled diabetes mellitus • Microvascular endothelial damage → tissue ischemia → necrosis • Suspect in diabetic pt with sudden onset muscle swelling & pain • Mean AIC: 9.3% with other diabetic complications • Common pattern: ↑CK, ↑ESR, ↑CRP • Diagnosis: MRI ↑signial intensity with inflammatory changes & edema • Tx: rest, analgesia (low dose ASA & NSAIDS), glycemic control (not surgery) • Average recovery 5.5 weeks with above treatment • High recurrence 35-48% in contralateral limb within 6 months - CMC IM Residency @CMC_IM #Diabetic #Myonecrosis #muscle #Infarction #diagnosis #management #diabetes