Diabetic Myonecrosis (Diabetic Muscle Infarction)
• Spontaneous ischemic necrosis of skeletal muscle (anterior thigh or calf)
• Rare complication of longstanding uncontrolled diabetes mellitus
• Microvascular endothelial damage → tissue ischemia → necrosis
• Suspect in diabetic pt with sudden onset muscle swelling & pain
• Mean AIC: 9.3% with other diabetic complications
• Common pattern: ↑CK, ↑ESR, ↑CRP
• Diagnosis: MRI ↑signial intensity with inflammatory changes & edema
• Tx: rest, analgesia (low dose ASA & NSAIDS), glycemic control (not surgery)
• Average recovery 5.5 weeks with above treatment
• High recurrence 35-48% in contralateral limb within 6 months
- CMC IM Residency @CMC_IM
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