Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency • Thalassemia: Alpha thalassemia, Beta thalassemia • Anemia of chronic inflammation (some patients) Normal MCV - 80 - 96 fL - "Normocytic" • Anemia of chronic kidney disease, Acute blood loss, Anemia of chronic inflammation (some patients), "Hospital-acquired anemia" High MCV - >96fL - "Macrocytic" • Megaloblastic: Vitamin B12 deficiency, Folate deficiency • Non-megaloblastic: Alcohol use, Liver disease (independent of alcohol use), Hypothyroidism, Myelodysplastic syndrome - Dr. Eric Strong @DrEricStrong - Strong Medicine https://www.youtube.com/c/EricsMedi #anemia #morphologic #mcv #differential #diagnosis #causes #hematology
