Magnesium Absorption and Pathophysiology Magnesium Absorption: • absorbed in the GIT — small intestine, Saturable active transcellular transport, Non-saturable passive paracellular transport Storage & Distribution • 99% in storage form in bone, skeletal and soft tissue, 1% in serum and red blood cell Excretion • 80% of absorbed magnesium is filtered • 90-95 % of filtered magnesium is reabsorbed • 3-5% excreted in urine • 15-20% is reabsorbed in PCT • 60-75% in thick ascending limb of loop of Henle • 5-10% in DCT NEPHKIDS 2020 @NEPHKIDS1 #Magnesium #Absorption #Pathophysiology #Mg #transport #nephrology
