Von Willebrand Disease Classification Type 1 (Accounts for ~3/4 of cases): • Defect: Quantitative defect (i.e. not enough VWF) • Inheritance: Autosomal dominant • Bleeding: None-severe Type 2 (Type 2A, 2B, 2M, 2N): • Defect: Qualitative defect (i.e. dysfunctional VWF) • Inheritance: Autosomal dominant (common), Autosomal recessive (uncommon) • Bleeding: Moderate-severe Type 3 (Accounts for <5% of cases): • Defect: Profound quantitative defect (i.e. a total or near total absence of vWF) • Inheritance: Autosomal recessive • Bleeding: Severe (Clinically similar to hemophilia A) - Dr. Eric Strong @DrEricStrong - Strong Medicine https://www.youtube.com/c/EricsMedi #VonWillebrand #Disease #Classification #Types #diagnosis #hematology
