Helpful Clues for Distinguishing Upper vs. Lower GI Bleeding Upper GI Bleed (proximal to ligament of Treitz): • Typically presents with hematemesis and/or melena. • Can present with hematochezia if the bleeding is very brisk. • Strong supporting features: - A "positive" gastric lavage - BUN/Cr ratio > 30 (using US units) • Notable risk factors: cirrhosis, alcohol, NSAlDs, H.pylori, hiatal hernia. Lower GI Bleed (distal to ligament of Treitz): • Typically presents with hematochezia. • Can present with melena if source is small intestines or ascending colon • Strong supporting feature: Blood clots mixed with the stool • Refuting feature: Hemodynamic instability - Dr. Eric Strong @DrEricStrong - Strong Medicine https://www.youtube.com/c/EricsMedi #Upper #Lower #GIBleed #comparison #versus #diagnosis #gastroenterology #ugib #lgib