Causes of Polyuria - Differential Diagnosis Excess Intake of Water: • Primary polydipsia (a.k.a. "psychogenic polydipsia") • Large volume IVF Excess Tubular Solute (a.k.a. osmotic diuresis): • Excess Na+: Conventional diuretics • Excess glucose: Poorly controlled diabetes mellitus, SGLT2 inhibitors (e.g. gliflozins) • Other: Mannitol Defect in Tubular Reabsorption of Water (a.k.a. Diabetes Insipidus): • Central Dl (Low production Of ADH): Idiopathic, Post-neurosurgery, Trauma, Infiltrative diseases, Hypoxic injury, Tumor • Nephrogenic DI (Renal resistance to ADH): Hereditary, Lithium, Hypercalcemia Polyuria Mimics (↑ urine frequency without ↑ urine volume): • UTI, BPH, Detrusor overactivity (a.k.a. "overactive bladder") - Dr. Eric Strong @DrEricStrong - Strong Medicine https://www.youtube.com/c/EricsMedi #Polyuria #Differential #Diagnosis #Causes #nephrology
