Eosinophilic Esophagitis (EoE) - Spectrum of Response
Non-response:
 • Histology: Persistent eosinophilia, ≥ 15 eos/hpf
 • Symptoms: Persistent symptoms, <30% decrease in a symptom metric
 • Endoscopy: Persistent endoscopic findings, <30% decrease in EREFS
Response:
 • Histology: Reduced eosinophilia, 7-14 eos/hpf 1-6 eos/hpf
 • Symptoms: Decreased symptoms, 30-90% decrease in a symptom metric
 • Endoscopy: Improved findings, EREFS score ≥2 but less than baseline
Complete Normalization:
 • Histology: Normal biopsy, <1 eos/hpf
 • Symptoms: Symptom resolution, >90% decrease in a symptom metric; EEsAl score < 20
 • Endoscopy: Normal esophagus, EREFS score < 2

#Eosinophilic #Esophagitis #EoE #Response #diagnosis #gastroenterology
Dr. Michael Chew @mchew85 · 4 years ago
GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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