Amebiasis - Acanthamoeba Life Cycle 1) Cysts 2) Trophozoite 3) Mitosis 4) Amebae (cysts and trophozoites) can enter humans in various ways 5) Through the eye - Results in severe keratitis of the eye. 6) Through nasal passages to the lower respiratory tract - Results in granulomatous amebic encephalitis (GAE) and/or disseminated disease in individuals with compromised immune systems. 7) Through ulcerated or broken skin - Results granulomatous amebic encephalitis (GAE), disseminated disease or skin lesions in individuals with compromised immune systems. #Amebiasis #Acanthamoeba #LifeCycle #diagnosis #pathophysiology #infectiousdiseases #cdc #parasite