Amebiasis - Naegleria fowleri - Life Cycle
1) Cysts
2) Trophozoite
3) Flagellated Form
4) Promitosis
→ Water-related activities such as swimming underwater, diving, or other water sports can result in water entering the nose →
5) Amebae penetrate the nasal mucosa
6) Amebae migrate to the brain via the olfactory nerves causing primary amebic meningoencephalitis (PAM) in healthy individuals
→ Trophozoites in CSF and brain tissue; flagellated forms occasionally in CSF
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