Algorithm for Metformin Prescribing and Dosing in CKD Dose Initiation - Immediate release: • Initial 500 mg or 850 mg once daily • Titrate upwards by mg/d or 850 mg/d every 7 days until maximum dose Dose Initiation - Extended release: • If Gl side effects from release • Initial 500 mg daily • Titrate upwards by 500 mg/d every 7 days until maximum dose #Metformin #Prescribing #Dosing #CKD #pharmacology #algorithm #diabetes #titration
