Longterm Venous Thromboembolism Treatment Algorithm
Treat for 3 months and reassess
• Isolated distal DVT (without cancer) - Stop at 3 Months
• Transient risk factor - Stop at 3 Months
• Cancer - Indefinite therapy or until cancer inactive
• Unprovoked proximal DVT or PE
- High Bleeding Risk OR Prefers to stop even if D-dimer or APA was positive - Stop at 3 Months
- Not High Bleeding Risk AND Prefers to stay on even if D-dimer was negative - Indefinite therapy
- Second VTE - Indefinite therapy
- Others - Stop and measure D-dimer and APA after 1 month
• Negative D-dimer and APA - Stay off therapy (Stop at 3 Months)
• Positive D-dimer or APA - Restart therapy (Indefinite therapy)
https://doi.org/10.1182/blood.20190
#Longterm #Venous #Thromboembolism #Treatment #Algorithm #management #hematology #anticoagulation
