DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban, Edoxaban or Rivaroxaban - Andexanet alfa - Recombinant modified factor Xa • Dabigatran - Idarucizumab - Humanized Fab fragment Prothrombin complex concentrate - If antidotes not available #DOAC #Reversal #NOAC #Oral #anticoagulant #hematology #management #pharmacology
