Effects on body weight of various classes of type-2 diabetes medications. - Metformin - Weight Loss + - SGLT-2 inhibitors - Weight Loss ++ - GLP-1 RAs - Weight Loss +++ - DPP-4 inhibitors - Neutral - Thiazolidinediones - Weight Gain + - Sulfonylureas - Weight Gain ++ - Insulin - Weight Gain ++++ #diabetes #weightloss #weightgain #comparison #pharmacology #medications