ABCs of Endoscopic Perforation Management A - Air by itself, not an adverse event. Control insufflation, ALWAYS use CO2 and if tension → Drain/Vent A - Antibiotics (broad spectrum) B - Bed position using gravity to minimize soilage C - Closure + Check (contrast study) D - Diversion of luminal contents (NPO+NGT and/or STENT) E - Evacuate collections (IR drains) F - Feeding/nutrition if prolonged NPO status → consider NJT F - Follow with CT/UGI and serial exams/WBC/CRP etc → Surgery - Gross soilage - Persistent contrast extravasation/failed closure - Sepsis #ABCs #endosopy #endoscopic #perforation #management #treatment #gastroenterology