Myoedema on Physical Exam Myoedema (or "mounding"): A sign of Hypothyroidism, refers to a small lump rising on the surface of a muscle when it is struck with a percussion hammer. It is characteristic of hypothyroid myopathy, lasts for 30-60 seconds It’s due to a sustained contracture associated with delayed relaxation, because of slow re-accumulation of calcium by the sarcoplasmic reticulum. Myoedema is not specific for hypothyroidism as it can also occur in hypoalbuminemia, rabies, severe cachexia, hyponatremia and renal failure. - Dr. Fatimah Dandan @FatimahDandan #Myoedema #PhysicalExam #clinical #neurology #hypothyroidism #video