Central vs Nephrogenic Diabetes Insipidus - Desmopressin Challenge
Give desmopressin (intranasal, SQ, IV) and monitor UOsm every 30 minutes over 2 hours
• No Rise in UOsm, still < 300 - Complete NDI
• Small < 45% rise in UOsm, still < 300 - Partial NDI
• Partial 15-50% rise in UOsm, > 300 - Partial CDI
• Rise in UOsm > 100% - Complete CDI
- VA Joint Chiefs @BostonChiefs
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