Central vs Nephrogenic Diabetes Insipidus - Desmopressin Challenge Give desmopressin (intranasal, SQ, IV) and monitor UOsm every 30 minutes over 2 hours • No Rise in UOsm, still < 300 - Complete NDI • Small < 45% rise in UOsm, still < 300 - Partial NDI • Partial 15-50% rise in UOsm, > 300 - Partial CDI • Rise in UOsm > 100% - Complete CDI - VA Joint Chiefs @BostonChiefs #Central #Nephrogenic #Diabetes #Insipidus #DI #Desmopressin #Challenge #diagnosis #nephrology #testing
