Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs, NSAIDs, calcineurin inhibitors (e.g. cyclosporine, tacrolimus) Intrarenal: • ATN: Aminoglycosides, cisplatin, tenofovir • AIN: Beta-lactams, vancomycin, sulfamethoxazole-trimethoprim (Bactrim), NSAIDs • Crystal nephropathy: Acyclovir, ganciclovir, ciprofloxacin, sulfamethoxazole, methotrexate Postrenal -↓ bladder sensation, impaired detrusor contraction, and/or ↑ urinary sphincter tone: • Opiates • Sympathomimetics (e.g. nasal decongestants) • Any drug with anticholinergic effects (e.g. antihistamines, TCAs, SSRIs, some antiemetics) - Dr. Eric Strong @DrEricStrong - Strong Medicine https://www.youtube.com/c/EricsMedi #AKI #Acute #Kidney #Injury #Medications #Drugs #pharmacology #differential #diagnosis
