Antiarrhythmics - Vaughan Williams Classification Class I (Ia, Ib, Ic) - Na+ Channel Blockade • Slows depolarization in fast AP cells • Widens QRS complex Class II - Beta Receptor Blockade • Slows depolarization in slow AP cells • Slows sinus rate and prolongs PR interval Class III - K+ Channel Blockade • Prolongs action potential • Prolongs QT interval Class IV - Ca2+ Channel Blockade • Slows depolarization in slow AP cells • Slow sinus rate and prolongs PR interval - Dr. Eric Strong @DrEricStrong - Strong Medicine https://www.youtube.com/c/EricsMedi #Antiarrhythmics #VaughanWilliams #Classification #Classes #cardiology #pharmacology
