Warfarin-Induced Skin Necrosis Aside from bleeding, the other major toxicity of warfarin is skin necrosis. Warfarin skin necrosis is exceptionally rare, but extremely disfiguring, and potentially life-threatening. The mechanism is related to the shorter half-life of the endogenous anticoagulant factor protein C, as compared to the procoagulant vitamin-K dependent factors. - Dr. Eric Strong @DrEricStrong - Strong Medicine https://www.youtube.com/c/EricsMedi #Warfarin #Induced #Skin #Necrosis #dermatology #rash #clinical
