Renal Tubular Acidosis - Differential Diagnosis Algorithm
Decreased Serum K, Urine pH < 5.5 - Proximal RTA
Decreased Serum K, Urine pH > 6.0 - Hypokalemic distal RTA
Increased Serum K = Hyperkalemic Renal Tubular Acidosis
• Urine pH < 5.5 - ↓ Aldosterone level or activity, Calcineurin inhibitors, Aldosterone antagonists, Pseudohypoaldosteronism, Urinary tract obstruction
• Urine pH > 6.0
- Tubulointerstitial injury: Urinary tract obstruction, Chronic interstitial nephritis, Sickle cell nephropathy
- Drugs that block ENaC: Amiloride, Triamterene, Pentamidine
Dr. Jain via UNC IM Chiefs @uncimchiefs
#RTA #Renal #Tubular #Acidosis #Differential #Diagnosis #Algorithm #nephrology
