Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics, Antimycobacterials, Amiodarone, Lithium • Toxins: Heavy metals, EtOH, Chemotherapy • Infectious: HIV, Hepatitis, Syphilis, Lyme disease, Leprosy • Inflammatory/AI: CIDP, Guillain-Barre, Vasculitis, Sjogren's, Lupus, Sarcoidosis, Amyloidosis • Malignancy: Paraprotein-associated (POEMS syndrome, myeloma, secondary amyloid), Paraneoplastic • Hereditary: Charcot-Marie-Tooth, Fabry's disease, Acute intermittent porphyria Dr. Leah Willis via UNC IM Chiefs @uncimchiefs #Peripheral #Neuropathy #differential #diagnosis #causes #neurology
