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Pitting vs Non-Pitting Edema: Differential Diagnosis For pitting edema: there's generally an issue with : ↑ Hydrostatic pressure ↓ Plasma oncotic pressure ↑ Vessel wall inflammation Non-pitting edema is usually caused by: ↑ increased protein secretion in the interstitium (i.e myxedema) - some issue with lymphatic drainage UTSWIM Chiefs @UTSWIMchief #Pitting #NonPitting #Edema #Differential #Diagnosis #causes