Streptocccus Pneumoniae Microbiology: Gram Positive, Alpha-hemolytic, Catalase Negative Epidemiology - 10% adult carriers: • Most common cause of: CAP, Bacterial meningitis, Otitis media • Important cause of sinusitis, septic arthritis, osteomyelitis, peritonitis, and endocarditis. Diagnosis: • Physical Exam, CXR, ENT exam, CT sinus • Sputum culture (Sensitivity 60%, Spec > 95%) • Urine antigen in CAP • Urine antigen in bacteremia (Sensitivity 82%, Specificity of 97%) Treatment: • B-Lactams (Penicillin/amoxicillin if sensitive) • Macrolide (addition might be associated with improved mortality in patients with bacteremia) Duration: PNA 5 days, Bacteremia 10-14 days, Meningitis 10-14 days, Endocarditis 4 weeks UTSWIM Chiefs @UTSWIMchief #Streptocccus #Pneumoniae #strep #microbiology #diagnosis #management
