Graves Disease - Autoimmune Hyperthyroidism Epidemiology: Most common cause of hyperthyroidism, Incidence peaks at 30-50 Diagnosis: 1 ) Primary hyperthyroidism 2) Measure thyrotropin-receptor antibodies 3) If 2 is negative, consider radioiodine uptake study. Clinical Presentation: • Hyperthyroidism: Fatigue, weight loss, tremor, palpitations, Goiter (younger>older), A Fib (older>younger) • Autoimmunity: Ophthalmopathy, Dermopathy, Acropachy Rx: • BB (beware contraindications) • Methimazole/PTU (take time) • Radioactive iodine (take time) • Thyroidectomy (goiter, or contraindications) UTSWIM Chiefs @UTSWIMchief #Graves #Disease #Autoimmune #Hyperthyroidism #diagnosis #management #endocrinology
