Serotonin Syndrome Drug Precipitants and Pharmacology ↑ Serotonin Formation: Tryptophan, Oxitriptan ↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine ↑ Serotonin Receptor Agonism: Buspirone, Triptans, Ergots, Fentanyl, Lithium ↓ Serotonin Metabolism (NAOI's): Selegiline, Methylene blue, Phenelzine, linezolid ↓ Serotonin Reuptake: SSRI's, SNRl's, Buproprion, Tricyclic Antidepressants, 5-HT antagonists (Ondansetron), Cyclobenzaprine, Cocaine, MDMA, Tramadol UCSD Internal Medicine @ucsdim #Serotonin #Syndrome #Pharmacology #medications #causes #differential #diagnosis #drug #Precipitants