Liposclerosing Myxofibrous Tumor (LSMFT) - MSK Radiology
Imaging Findings:
• Geographic lucent lesion with sclerotic margin in the intertrochanteric region of the right femoral neck.
• Low signal sclerotic rim with high-signal on T2-sequences and isointense to muscle on T1-sequence. There is homogenous post-contrast enhancement of the lesion.
Case description:
• Rare fibro-osseous bone lesion with propensity for intertrochanteric region of femur (80-90%).
• Despite its name; distinct fatty components or fat signal not seen.
• Potential for malignant transformation (10-15%).
- Follow-up imaging is preferable with MRI to evaluate for interval change. If change or symptoms → surgical tx.
Differential diagnosis for bone lesion:
• Fibrous dysplasia: more low-signal intensity on fluid sensitive MRI sequences.
• Intraosseous lipoma: Usually has macroscopic fat; whereas LSMFT do not typically have obvious lipomatous components.
• Aneurysmal bone cyst: expansile.
Dr. Donald von Borstel @DrvonBorstel
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