Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment: • Common bacteria (endogenous): Streptococci (oral), Staphylococci (skin), Gram-negative bacilli (gut), Clostridioides difficile (gut) • Fungi: Candida spp. (mucosa), Aspergillus spp. (airways) • Viruses: HSV (reactivation), RSV Early Post-Engraftment: • Viruses: CMV (reactivation), VZV (reactivation), HHV-6, Adenovirus, RSV • Fungi: Aspergillus spp. (airways), Pneumocystis jirovecii (airways) • Protozoa: Toxoplasma gondii Late post-engraftment: • Bacteria (encapsulated): Streptococcus pneumonia, Staphylococcus aureus • Viruses: VZV (reactivation), CMV (reactivation), RSV • Fungi: P. jirovecii (airways) • Protozoa: T. gondii #Transplant #Infections #Timeline #differential #diagnosis #causes #infectiousdiseases
