Smoking Cessation Management Nicotine Replacement Therapy (NRT): Long-Acting NRT: • Patch: Wear for 24 hours at a time. Alternate sites to minimize skin irritation. Short-Acting NRT (Combine with nicotine patch for best effect): • Mini Lozenge: Allow to slowly dissolve. Do not chew or swallow lozenge. • Gum: Chew minimally, "park" between teeth and cheek. Rechew when tingling is gone and rotate sites. Avoid use with acidic foods. • Nasal Spray: Can be used once to each nostril every 1-2 hours. Non-nicotine Replacement Therapy: • Varenicline (Chantix): Nicotinic receptor partial agonist designed to decrease cravings, reduce withdrawal, and dampen nicotine-induced reward pathway • Bupropion (Wellbutrin): Nicotinic receptor antagonist and norepinephrine & dopamine reuptake inhibitor. Designed to reduce cravings and withdrawal. Electronic Cigarettes: Reserve use until after FDA-approved treatments have failed. CORE IM Podcast @COREIMpodcast #Smoking #Cessation #Management #pharmacology #addition #tobacco