Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 • Urgent condition due to severe compression of nerve roots of lumbar spine
 • MCC- acute lumbar disc herniation
 • Involves lumbar spine L1-L5

Symptoms - Cauda equina syndrome (CES) is usually characterized by these so-called ‘red flag’ symptoms:
 • Severe low back pain (LBP)
 • Sciatica: often bilateral but sometimes absent, especially at L5/S1 with an inferior sequestration
 • Saddle and/or genital sensory disturbance
 • Bladder, bowel and sexual dysfunction
SPINE Mnemonic:
 • S - Saddle anesthesia
 • P - Pain
 • I - Incontinence
 • N - Numbness
 • E - Emergency

Causes of Cauda Equina Syndrome:
 • large lower lumbar disc herniation, prolapse or sequestration
 • epidural hematoma
 • infections
 • primary and metastatic neoplasms
 • trauma
 • post surgical
 • prolapse after manipulation
 • after chemonucleolysis
 • after spinal anaesthesia
 • ankylosing spondylitis
 • gunshot wounds
 • constipation

Differential Diagnosis:
 • Spinal cord infarct
 • HIV related myelopathy
 • Transverse myelitis
 • Multiple sclerosis
 • Syringomyelia
 • Spinal AVM
 • Multilevel lumbar stenosis
 • Vascular intermittent Claudia toon
 • Spinal infection/abscess
 • Ankylosing spondylitis
 • Tethered cord
 • Guillain-Barre syndrome
 • Neurosarcoidosis
 • Multiple sclerosis
 • Diastematomyelia

Physical Exam:
 • Inspection
	- lower extremity muscle atrophy
 • Palpation
	- lower back pain/tenderness is not a distinguishing feature
	- palpation of the bladder for urinary retention
 • Neurovascular Examination
	- bilateral or unilateral lower extremity weakness and sensory disturbances
	- decreased or absent lower extremity reflexes
	- reduced or absent sensation to pinprick in the perianal region (S2-S4 dermatomes), perineum, and posterior thigh
	- decreased rectal tone or voluntary contracture
 • Provocative Tests
	- diminished or absent bulbocavernosus reflex
	- diminished or absent anal wink test
	- reflex contraction of the external anal sphincter upon pinprick stimulation of skin around the anus

Laboratory studies:
 • CBC, ESR, CRP
 • Urodynamic studies (PVR)

Imaging studies:
 • MRI- Sagittal, axial T1 and T2

Treatment:
 • Surgical decompression

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Ravi Singh K @rav7ks · 3 years ago
Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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