Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without other constituents. Non-specific, but can be seen in dehydration. • "Muddy Brown" Casts - Strongly suggestive of acute tubular necrosis (ATN) • Waxy Casts - Non-specific; seen in a variety of acute and chronic kidney diseases • Fatty Casts - Contains yellow-tan fat globules. Strongly suggestive of nephrotic sydnrome • Pigment Casts - Contains one of several colored compounds (e.g. heme, bilirubin, etc...) • Granular Casts - Believed to be from degeneration of a cellular cast Cellular Casts: • RBC Casts - Strongly suggestive of glomerulonephritis • WBC Casts - Strongly suggestive of interstitial inflammation (which can be either infectious or non-infectious) - Dr. Eric Strong @DrEricStrong - Strong Medicine https://www.youtube.com/c/EricsMedi #Casts #Urine #Microscopy #nephrology #interpretation #diagnosis