CGD and Mulch Pneumonitis This acute fulminant invasive fungal pneumonia in absence of iatrogenic or exogenous immunosuppression is a medical emergency highly associated with CGD Exposure such as: Cleaning gutters with dead leaves; Mulching; Wood chipping; Lawn mowing High level exposure to aerosolized fungal spores and hyphae Acute dyspnea, hypoxia, fever, and evidence of pulmonary infiltrates Can progress to fulminant respiratory failure and death within 1-10 days Manage with glucocorticoids and antifungal therapy By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com] #CGD #Mulch #Pneumonitis #chronic #granulomatous #disease #diagnosis