Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
- 70%; IgG mediated
- DAT: IgG positive, C3 positive or negative
- Smear: spherocytes
Cold AIHA:
- 20%; IgM mediated
- DAT: IgG negative, C3 positive
- Smear: agglutination, rouleaux
BWH Medicine Residency @BrighamMedRes
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