Antithrombotic Therapy in Patients with Prosthetic Heart Valves - INR Targets Mechanical Valve - Duration Lifelong INR 3.0: • Any mitral valve prosthesis • Aortic valve prosthesis (bileaflet or current-generation single-tilting disc) WITH risk factors for thromboembolism (atrial fibrillation, prior thromboembolism, LV dysfunction, hypercoagulable state) • Older generation aortic valve prosthesis (ball-in-cage) INR 2.5: • Aortic valve prosthesis WITHOUT risk factors for thromboembolism (atrial fibrillation, prior thromboembolism, LV dysfunction, hypercoagulable state) Bioprosthetic Valve - Duration: at least 3 months - as long as 6 months • Aortic or Mitral Valve Dr. Patrick Ching @patrickching #INR #Targets #Goals #anticoagulation #warfarin #coumadin #Prosthetic #mechanical #Heart #Valves #cardiology