Polyuria - Differential Diagnosis Algorithm Polyuria = >3L Urine output / 24 hours Urine osmolality = 2 (Na meq/L + K meq/L] + [BUN mg/dL]/2.8 + [glucose mg/dL]/18 HIGH urine osmolality > 300 mosm/kg • Solute Diuresis: Hyperglycemia, High solute intake (e.g. IV fluids, nutrition), Azotemia LOW urine osmolality < 100 mosm/kg • Diabetes Insipidus • Primary Polydipsia #Polyuria #Differential #Diagnosis #Algorithm #nephrology
