DDAVP Clamp Protocol in Hyponatremia • Stop any maintenance fluids. • Start DDAVP 2 mcg IV q8h • Start 3% NaCl (1-1.5 ml/kg over 6 hours) • Fluid restrict patient to 1.2 liters per day • Monitor sodium every 2 hours initially. Once the sodium is rising predictably, decrease frequency to every 4-6 hours. • Adjust 3% NaCl infusion rate to achieve correction of less than 8 mmol/L per day. Try to avoid adjusting the rate more than every 6 hours. Look at the sodium trend rather than the latest value. • Continue 3% and DDAVP until the sodium is 125-130 #DDAVP #Clamp #Protocol #Hyponatremia #management #nephrology
