Syncope - Differential Diagnosis Framework Reflex Syncope: • Vasovagal: Prolonged standing, Stress, Pain • Situational: Coughing, Sneezing, Micturition, Defecation, Post-exercise • Carotid sinus: hypersensitivity Orthostatic Syncope: • Volume Depletion • Medication Effect: a-blockers, antidepressants, antipsychotics • Autonomic Failure: Parkinson's, Diabetes, Alcoholism, Amyloidosis, Multiple System Atrophy Cardiogenic Syncope: • Bradyarrhythmias: Sinus bradycardia, Sinus pauses, AV block • Tachyarrhythmias: Ventricular • Mechanical: Aortic stenosis, HOCM, PE Syncope Mimics: • Seizure • "Cerebrovascular Syncope": Vertebrobasilar insufficiency, Subclavian steal syndrome • Alcohol "blackout" • Sedation • Psychogenic pseudosyncope SCVMC Internal Medicine @SCVMCMed #Syncope #Differential #Diagnosis #mimics
