Gout - Management Acute Gout Flare 1) colchicine, NSAIDs, glucocorticoids 2) Anakinra (IL-1 inhibitor) When to Start Urate Lowering Therapy (ULT) 1) presence of tophi 2) radiologic damage 2/2 gout 3) 2+ gout flares/year 4) consider with 1st flare if sUA >9, CKD ≥3, or urolithiasis Urate Lowering Therapy: 1) allopurinol 2) febuxostat (Uloric) 3) pegloticase Mithu Maheswaranathan, MD @MithuRheum #Gout #Management #treatment #rheumatology