Cardiac Amyloidosis Management The liver produces transthyretin tetramers, which dissociate into monomers and mis-fold, then aggregate into amyloid fibrils and deposit into cardiac tissue. Cardiac amyloidosis leads to restrictive cardiomyopathy, presenting similarly to heart failure; however, there are several differences in treatment approaches. by YeeAnn Chen, PharmD @yeeann_c #Cardiac #Amyloidosis #Management #tafamidis #Treatment
