Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for the liver
ALP - Biliary tree or bile flow abnormality vs bone
Bili - Direct (Obstructive) vs Indirect (Hemolytic)
Hepatocellular Pattern - Transaminase >> Alkaline Phosphatase, ALT ≥ 3x ULN
Cholestatic Pattern - Alkaline Phosphatase >> Transaminase, ALP ≥ 2x ULN
R Value = (ALT / ULN ALT) / (ALP / ULN ALP)
≥5: Hepatocellular injury
>2 to ≤ 5: Mixed pattern
≤2: Cholestatic injury
Sinai Hospital of Baltimore IM Residency @SinaiBmoreIMRes
#Liver #FunctionTest #LFTs #Elevation #Transaminitis #diagnosis #hepatology
