Legionnaires' Disease Clinical features: • Gl- nausea, vomiting, diarrhea • Hyponatremia • Elevated transaminases • CRP >100 • Failure to respond to B-Lactams Treatment: • Levofloxacin • Azithromycin • Alternatives- Other FQ macrolides or tetracyclines Duration: • Minimum 5 days (mild) • At least 7-10 days- severe or comorbidities • Immunocompromised- 14 days minimum Other Legionella Infections: 1. Pontiac fever 2. Extra-pulmonary: cellulitis, septic arthritis, OM, myocarditis, pericarditis, meningitis, pyelonephritis (immunocompromised patients) Sinai Hospital of Baltimore IM Residency @SinaiBmoreIMRes #Legionnaires #Disease #diagnosis #management
