Varicella Zoster Virus (VZV) - Post-Exposure Prophylaxis
Varicella or Disseminated Zoster:
• Transmission: direct contact w/ fluid of vesicles or inhalation of aerosols
• Exposure: non immune person has face-to-face contact w/ pt for >5 minutes
• Timeline: 1-2d pre rash until lesions crusted
Localized Zoster:
• Transmission: direct contact w/ fluid of vesicles
• Exposure: non-immune person has direct contact w/ pt (e.g., vesicles)
• Timeline: until lesions crusted
PEP = varicella vaccination w/in 5d if eligible to receive
• 90% efficacy if given by 3d, 70% efficacy if given by 5d
• ELIGIBILITY FOR VACCINATION as prophylaxis:
- Age >12mo, not pregnant
- Not immunocompromised
- No history of severe reaction to varicella vaccine or component
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