Indications for Irradiated Blood Product Transfusion Irradiation of blood is performed for only one reason: to prevent transfusion-associated graft-versus-host-disease (TA-GVHD). Patients with HIV infection do not get TA-GVHD and should NOT receive irradiated blood. • Absolute Indications: Stem Cell Transplant Patients, Congenital immune deficiencies, Intrauterine transfusion, Transfusion from relatives, Hodgkin's disease (even in remission!) • Probable indications: Hematological malignancies other than Hodgkin's disease, Patients receiving aggressive chemotherapy Dr. Thomas DeLoughery @Bloodman #Indications #Irradiated #BloodProduct #Transfusion #management