NAFLD / NASH Progression Timeline Healthy Liver → NAFLD/NASH → 0.25-3.2%/year → Cirrhotic NASH → 0.3-2.6%/year → HCC • NAFLD/NASH → Cirrhotic NASH Risk Factors: Obesity, Arterial hypertension, Diabetes, Dyslipidemia, PNPLA3/TM6SF2 Polymorphisms, Gut microbiota, Dietary habits • Cirrhotic NASH → HCC Risk Factors: Obesity, Diabetes, Advanced fibrosis, PNPLA3/TM6SF2 Polymorphisms, Age #NAFLD #NASH #Progression #Timeline #hepatology
