Causes of Small Bowel Ulceration The diagnosis of IBD can’t be made or excluded by biopsies alone - this requires clinical and endoscopic correlation. Causes of ulceration depends on the site - here’s a list of causes in the small bowel. • Infection: Salmonella, Parasites, Histoplasma, HIV, Cryptococcus, CMV, C. diff. • Enteritis: Crohn's, Coeliac, Radiation, Immune (Eosinophilic, CVID, Hyper IgD, Mastocytosis) • Vascular: Ischaemia, Vasculitis, Behcet's / SLE, Aortoenteric fistula • Neoplasia: NET, GIST, Lymphoma, Metastases, Zollinger-Ellison, Adenocarcinoma • Drugs: NSAIDs, Aspirin, Checkpoint inhibitors, Arsenic • Others: Amyloidosis, Mechanical, Endometriosis, Idiopathic (CMUSE) By Keith Siau @drkeithsiau #SmallBowel #Ulceration #diagnosis #differential #gastroenterology
