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Mesalamine (Mesalazine) Therapy Simplified by Location Orals - Terminal Ileum, Ascending Colon, Transverse Colon Enemas - Reach the splenic flexure Foams - Reach the sigmoid colon Suppositories - Rectum and 15 cm beyond anal verge Dr. Keith Siau @drkeithsiau #Mesalamine #Mesalazine #IBD #pharmacology #administration #Location #management