Volume Based Approach to Hyponatremia Hypovolemic, Serum uric acid >4 • Urine Na <20: Extra-renal losses • Urine Na >30: Renal losses, Cerebral salt wasting Euvolemic, Serum uric acid <4 • SIADH, Hypothyroidism, Low solute intake, Glucocorticoid deficiency, Primary polydipsia Hypervolemic, Serum uric acid >4 • Urine Na < 20: Heart failure, Cirrhosis, Nephrotic syndrome • Urine Na > 30: Renal failure Satya Patel, MD @SatyaPatelMD #Volume #Hyponatremia #algorithm #diagnosis #sodium #low #nephrology
